Novo Nordisk employee
Novo Nordisk employee

Ongoing focus

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At Novo Nordisk®, we believe that the formula for lasting success is to stay focused, think long-term, and do business in a financially, socially, and environmentally responsible way.

Product portfolio

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We aspire to be a respected leader in the health care industry, helping patients with treatments for:

  • FVII deficiency
  • FVIII deficiency
  • FVIII deficiency with inhibitors
  • FIX deficiency
  • FIX deficiency with inhibitors
  • FXIII deficiency
  • Glanzmann’s thrombasthenia with refractoriness to platelet transfusions, with or without antibodies to platelets
  • Acquired hemophilia

Environmental awareness

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We also strive to minimize the environmental impact of our activities. Our facilities in Denmark supply quality products in a socially responsible and environmentally sound way, using 100% renewable energy.1

The Triple Bottom Line.

The Triple Bottom Line (TBL) is Novo Nordisk’s way of doing business. We believe that a healthy economy, environment, and society are fundamental to long-term business success. We are one of only four companies in the world who have incorporated our philosophy into our company bylaws.

Everything we do and every decision we make is informed by the three pillars of TBL:

Social impact.

Social responsibility is about caring for people. This applies to the people who depend on our products, as well as to our employees. We work to continuously integrate social, health, and safety considerations into our daily business.


Environmental responsibility.

Environmental soundness addresses our impact on the external environment – and we’ve taken a concerted approach to ensure that our efforts to be green pay off.

The campus of our LEED Silver certified U.S. Headquarters demonstrates our approach to being responsible stewards of our environment, driven by the company’s commitment to help people live healthy lives, and consistent with Novo Nordisk’s TBL business model.

Our campus utilized recycled and locally-sourced materials, and is fully powered by renewable energy from wind, solar, and hydro sources—a feature that is expected to lead to a 30 percent reduction in energy costs.


Financial performance.

Economic viability is about managing the business in a way that secures growth and value creation, and delivers competitive performance in these areas. Investing in our employees contributes to our award-winning workplace and supports our goal of delivering innovative achievements.

As of August 2017, Novo Nordisk Inc. has been ranked in Fortune Magazine’s Best Places to Work listing every year since 2009. Most recently, Novo Nordisk was presented with the New Good Neighbor Award by the New Jersey Business & Industry Association. This award was based on a variety of factors, including economic benefit/job creation, architectural merit, and community involvement.

Novo Nordisk is also committed to investing in Research and Development. In 2016, 13% of sales went towards funding R&D projects across the organization.

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Selected Important Safety Information

Contraindications

  • Rebinyn® is contraindicated in patients with a known hypersensitivity to Rebinyn® or its components, including hamster proteins.

Warnings and Precautions

Hypersensitivity reactions, including anaphylaxis, may occur. Signs may include angioedema, chest tightness, difficulty breathing, wheezing, urticaria, and itching. Discontinue Rebinyn® if allergic or anaphylactic type reactions occur and initiate appropriate treatment.

Indications and Usage

Rebinyn®, Coagulation Factor IX (Recombinant), GlycoPEGylated, is a recombinant DNA derived coagulation Factor IX concentrate indicated for use in adults and children with hemophilia B for on-demand treatment and control of bleeding episodes and perioperative management of bleeding.

Limitations of Use: Rebinyn® is not indicated for routine prophylaxis or for immune tolerance induction in patients with hemophilia B.

Important Safety Information

Contraindications

  • Rebinyn® is contraindicated in patients with a known hypersensitivity to Rebinyn® or its components, including hamster proteins.

Warnings and Precautions

  • Hypersensitivity reactions, including anaphylaxis, may occur. Signs may include angioedema, chest tightness, difficulty breathing, wheezing, urticaria, and itching. Discontinue Rebinyn® if allergic or anaphylactic-type reactions occur and initiate appropriate treatment.
  • Development of neutralizing antibodies (inhibitors) to Factor IX  may occur. Monitor patients for development of Factor IX inhibitors if bleeding is not controlled with the recommended dose of Rebinyn® or if expected Factor IX activity plasma levels are not attained. Factor IX activity assay results may vary with the type of activated partial thromboplastin time reagent used.
  • The use of Factor IX-containing products has been associated with thrombotic complications. Monitor for thrombotic and consumptive coagulopathy when administering Rebinyn® to patients with liver disease, post-operatively, to newborn infants, or to patients at risk of thrombosis or disseminated intravascular coagulation (DIC).
  • Nephrotic syndrome has been reported following immune tolerance induction therapy with Factor IX products in hemophilia B patients with Factor IX inhibitors, often with a history of allergic reactions to Factor IX. The safety and efficacy of using Rebinyn® for immune tolerance induction have not been established.

Adverse Reactions

  • The most common adverse reactions reported in clinical trials (≥1%) were itching and injection site reactions.
  • Animals administered repeat doses of Rebinyn® showed accumulation of PEG in the choroid plexus. The potential clinical implications of these animal findings are unknown.

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Reference

  1. Data on file. Novo Nordisk Inc., Plainsboro NJ.