REBINYN® may reduce the need for additional infusions6,a,b,c
Time (days)
Plasma Activity (U/dL or IU/dL)
Rebinyn®
WFH target FIX
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begin
begin
Total
dosage
dosage
0
IU/kg6
Total infusions
0
Total infusions
0
Plasma Activity (U/dL or IU/dL)
SHL
WFH target FIX
rFIX
pdFIX
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begin
begin
Total
dosage
dosage
0
IU/kg6
Dashed lines=mean predicted FIX activity; shaded regions=95% confidence intervals for FIX activity. | |
a | A single dose should be enough for minor and moderate bleeds. Your doctor may recommend additional doses of 40 IU/kg.6 |
b | Based on a pharmacokinetic (PK) modeling to World Federation of Hemophilia (WFH) guidelines. Simulated results based on phase 1 PK study of Rebinyn® (n=15), recombinant FIX (rFIX) (n=7), and plasma-derived FIX (pdFIX) (n=8).6 |
c | Compared with SHL products.6 |
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